Setup Outlook Out of Office Message on Mac

Open Outlook and go to Tools in the top left of the screen

From Tools, select Out of Office

This will prompt a pop-up window with the options for your message. In the “Reply once to each sender with:” field, type your out of office message. Underneath that box there will be a check box for “Only send replies during this time period:” where you can select the dates and times that you want the message to start sending and stop sending. If you leave this unchecked, your out of office message will send until you turn it off.